Numerical study of the effect of methemoglobin concentration in the blood on the absorption of light by human skin

Lasers are widely used in dermatology to remove telangiectasias. Increasing the efficiency of sclerosis deep-lying and large telangiectasias with laser radiation is possible by changing optical transmission skin when it heated converting hemoglobin blood contained into methemoglobin. The influence concentration methemoglobin on absorption light human poorly understood, which determines relevance this study context finding ways improve removal Seven-layer models without telangiectasia for numerical simulation were developed. extinction coefficients degree change whole layers calculated range wavelength from 400 1600 nm model arteriolar venular at various concentrations blood. Based analysis these data, wavelengths biggest occurred during transformation selected. At selected wavelengths, Monte Carlo method was modelling get distribution absorbed power each layer It has been shown that spectra do not differ significantly. During methemoglobin, largest decrease occurs 629 1105 nm, increase 447 578 nm. part superficial vascular plexus increases, 441 574 decreases a growth 0 100 % model. same time, deep value increases but first up 25 %, then decreases, values exceeding associated replacement more pronounced layer, high content limited contribution overlying deformation spectrum incident layer. In telangiectasia, changes proportion greater amount than can be an volume their thickness. obtained results applied development systems technologies treatment diseases, including